Hello.
What are the e2 blood test values? What dose of testosterone are you using?
×
▼ Click to expandLast cycle I was on 300mg Enanthate weekly and e2 side effects (sensitive nipples) were starting on 400mg, I had no problems on 300mg and I don't really plan on going above that but I think I should still have Inhibitor ready just in case... I no longer have the bloodwork from the cycle unfortunately.
×
blood test before taking medication or adding a 2nd injectable that manages e2 !My questions: Which should I consider? Anastrozole maybe?
How you use it (dosage and when)?
And Side effects to be known.....
×
Last cycle I was on 300mg Enanthate weekly and e2 side effects (sensitive nipples) were starting on 400mg, I had no problems on 300mg and I don't really plan on going above that but I think I should still have Inhibitor ready just in case... I no longer have the bloodwork from the cycle unfortunately.
Masteron does not inhibit aromatase, because unlike primo and EQ, it doesn't have the double bond at position one. It maybe antagonises estrogens at estrogen receptor alpha at high doses (competitive inhibitor). On the other hand, nandrolone seems to upregulate aromatisation (it speeds it up).Otherwise the injectables that you add to the testosterone like primo, boldo or mast which manage the e2 more or less .
Mast will manage more or less depending on the dose and the person. There is no single dose limit.Masteron does not inhibit aromatase, because unlike primo and EQ, it doesn't have the double bond at position one. It maybe antagonises estrogens at estrogen receptor alpha at high doses (competitive inhibitor). On the other hand, nandrolone seems to upregulate aromatisation (it speeds it up).
Do you have any bloodwork to share? Mechanistically, we have zero clue why masteron would reduce estradiol, but EQ and primo have the double bond at position 1 (similarly to exemestane and testolactone). I can share a few bloodworks (from about 3 different people) that prove primo reduces estradiol and masteron does not. Best case scenario, masteron just inhibits some activity on estrogen alpha receptors, but that doesn't show on bloodwork.Mast will manage more or less depending on the dose and the person. There is no single dose limit.
As I said, primo boldo mast manage the e2 more or less.
Of course, less for the mast and more for the other 2
I'm just telling you that some people with a high dose of mast have their e2 levels drop. Why, I don't know, on paper as you say it doesn't cut the aromatization, I'll give you some informationDo you have any bloodwork to share? Mechanistically, we have zero clue why masteron would reduce estradiol, but EQ and primo have the double bond at position 1 (similarly to exemestane and testolactone). I can share a few bloodworks (from about 3 different people) that prove primo reduces estradiol and masteron does not. Best case scenario, masteron just inhibits some activity on estrogen alpha receptors, but that doesn't show on bloodwork.
Maybe they dropped e2 because they got leaner. That's why anecdotes are usually problematic: the variables are not all under control. Masteron is usually used in cutting cycles, so the people you mentioned probably lost bodyfat. This happened to one of my clients.I'm just telling you that some people with a high dose of mast have their e2 levels drop. Why, I don't know, on paper as you say it doesn't cut the aromatization, I'll give you some information
Yes, I know, that's normal….Maybe they dropped e2 because they got leaner. That's why anecdotes are usually problematic: the variables are not all under control. Masteron is usually used in cutting cycles, so the people you mentioned probably lost bodyfat. This happened to one of my clients.
i agree with you. Masteron is not AI and it actually even might raise e2 because it will binds to shbg and raise free test and consequently potentialize aromatization. But it will feel like anti estrogen because it will also compete with e2 for the estrogen receptors. You actually will feel dry but with high e2. Do you know if there is any dangerous to this? i assume is going to compromise sexual function but does it have a more dangerous side effect?Maybe they dropped e2 because they got leaner. That's why anecdotes are usually problematic: the variables are not all under control. Masteron is usually used in cutting cycles, so the people you mentioned probably lost bodyfat. This happened to one of my clients.
Maybe it's even not dangerous, since the estrogen alpha receptor is only "responsible" for feminising effects. Don't know about libido changes, my client who is on 175 test e and 700 mast e had zero complaintsDo you know if there is any dangerous to this? i assume is going to compromise sexual function but does it have a more dangerous side effect?
Yes, to a point, but free testosterone will aromatise even if it does not saturate all androgen receptors, so I don't think the assessment is correct here. It's the androgenic side effects (the non genomic effects) that signify the androgen dose is too high and testosterone will aromatise before that.The target always should be to find a dosage with good result without needing pharmaceutical estrogen management (you should have some as a backup if something goes wrong) - it's not the target to use much more than you would need and manage the problems adding estrogen inhibiting products (or prolactin inhibiting products).
Of course, testosterone aromatizes even when receptors are not saturated; otherwise, no normal man would have even a microgram of estrogen, etc., in his body, which would be fatal. However, the key here is to find the right amount of exogenous testosterone so that aromatase doesn't exceed normal levels too much.Yes, to a point, but free testosterone will aromatise even if it does not saturate all androgen receptors, so I don't think the assessment is correct here. It's the androgenic side effects (the non genomic effects) that signify the androgen dose is too high and testosterone will aromatise before that.
I agree on the low e2 being bad, but I do think you can have too much aromatisation on a dose of testosterone, that is not maxxed out (meaning you would still get more anabolism from raising the dose)Of course, testosterone aromatizes even when receptors are not saturated; otherwise, no normal man would have even a microgram of estrogen, etc., in his body, which would be fatal. However, the key here is to find the right amount of exogenous testosterone so that aromatase doesn't exceed normal levels too much.
To be honest; I'm always very sceptical when somes asks questions concerning "managing estrogen while test-cycle". The reason is quiet simple: Not only too low testosteron f.e. after a cycle can cause problems, too low estrogen levels within the cycle can cause even worse problems.