HGH timing

[Falcon]

I read that most people inject HGH in the evening. What is the rationale behind that? There is a natural surge in growth hormone at night, so it seems to me that adding exogenous hormone on top of that can be superfluous, or possibly tell our bodies that the natural release is not needed. Is there a reason to use it before bed? I used up one package so far, and used it in the morning up to around noon. I'm wondering if I should experiment with evening use in the future, but I don't want to waste the natural hormone release. After the age of 50-60, it makes sense to switch to evening use, because natural GH production decreases and we would just replace the normal nighttime GH our bodies expect. Hope that makes sense. So please tell me the aspects I may have forgot to consider here.

 

[Bodykris]

The scientific point is that GH is not secreted continuously, but in pulses, under the balance of GHRH / somatostatin / ghrelin, with feedback regulation via IGF-1. So exogenous GH does not simply “leave the night untouched” if you shift the timing: it already acts on the GH/IGF-1 axis and tends to suppress endogenous secretion .So personally, morning or evening is not very important.

 

[Falcon]

The scientific point is that GH is not secreted continuously, but in pulses, under the balance of GHRH / somatostatin / ghrelin, with feedback regulation via IGF-1. So exogenous GH does not simply “leave the night untouched” if you shift the timing: it already acts on the GH/IGF-1 axis and tends to suppress endogenous secretion .So personally, morning or evening is not very important.

Thank you for the clarification. Not so good news if in terms of increasing total GH effect, but it means I can safely try it the evening next cycle.

 

[Donvitosharkone]

I read that most people inject HGH in the evening. What is the rationale behind that? There is a natural surge in growth hormone at night, so it seems to me that adding exogenous hormone on top of that can be superfluous, or possibly tell our bodies that the natural release is not needed. Is there a reason to use it before bed? I used up one package so far, and used it in the morning up to around noon. I'm wondering if I should experiment with evening use in the future, but I don't want to waste the natural hormone release. After the age of 50-60, it makes sense to switch to evening use, because natural GH production decreases and we would just replace the normal nighttime GH our bodies expect. Hope that makes sense. So please tell me the aspects I may have forgot to consider here.

honestly, go simple.

Use the minimum before bed, and before fasted activity or PWO.

All the rest is essentially overthinking, what matter the most is consistency, rather than specifities.

Hope it helps

Shark